Vaccine stops urinary tract infections for up to nine years

Vaccine stops urinary tract infections for up to nine years
Pssst. Splat. (Image: LU)

“Recurring urinary tract infections (UTIs) can be prevented for up to nine years with an oral spray vaccine, a landmark British trial has shown. Experts said the treatment was a ‘game changer’ for people suffering from continual painful infections,” which cause 150,000 hospitalizations every year in the United Kingdom alone, reports The Telegraph.

“Around half of women and 20 per cent of men suffer UTIs, which can be particularly dangerous for older people, causing irregular heartbeat, high blood pressure, and triggering potentially lethal falls,” The Telegraph says:

The death rate for hospital UTIs is four in 100, accounting for around 6,000 deaths a year. It rises to one in 10 for people aged 95 and over as it can often develop into sepsis and make dementia worse.

In a long-running trial, 89 patients were asked to spray the pineapple-flavoured vaccine under their tongue every day for three months, and then followed up for nine years by clinicians at the UK’s Royal Berkshire Hospital. Nearly half of the participants (48 per cent) remained entirely infection-free during the nine-year follow-up. The average infection-free period across the cohort was 54.7 months (four and a half years) – 56.7 months for women and 44.3 months, one year less, for men.

Dr. Bob Yang, who led the research, stated that “Before having the vaccine, all our participants suffered from recurrent UTIs, and for many women, these can be difficult to treat. Nine years after first receiving this new UTI vaccine, around half of the participants remained infection-free. Overall, this vaccine is safe in the long term and our participants reported having fewer UTIs that were less severe. Many of those who did get a UTI told us that simply drinking plenty of water was enough to treat it.” Yang is a urologist with the Royal Berkshire NHS Foundation Trust.

Currently, urinary tract infections are treated with antibiotics, but antibiotic-resistant infections have increased and antibiotics have become less effective as a result.

The vaccine, called Uromune, was developed by the Spanish drugmaker Immunotek. It contains whole bacteria of the four most common germs that cause urinary tract infections in patients of both sexes: Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris and Enterococcus Faecalis. The vaccine is licensed in Spain, but it is not yet approved for use by Britain’s National Health Service.

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Hans Bader

Hans Bader

Hans Bader practices law in Washington, D.C. After studying economics and history at the University of Virginia and law at Harvard, he practiced civil-rights, international-trade, and constitutional law. He also once worked in the Education Department. Hans writes for CNSNews.com and has appeared on C-SPAN’s “Washington Journal.” Contact him at hfb138@yahoo.com

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