By Natalie Sandoval
Evidence-based? Maybe. Thorough? Definitely not.
Dr. Gordon Guyatt, who coined the term “evidence-based medicine” in 1991, appeared on the Beyond Gender podcast to discuss his work. Guyatt signed a letter Aug. 14 claiming, “It is unconscionable to forbid clinicians from delivering gender-affirming care. ”
“You have signed this statement that says … this [gender-affirming care] is ‘medically necessary,’” co-host and researcher Mia Hughes began.
“How ridiculous,” Guyatt interrupted. “We never said anything … I would never use the term ‘medically necessary’ … I would never use it, the fact that you just said we said it was ‘medically necessary’ is completely wrong.” (RELATED: Doctors Quietly Admit They Cheat All The Time)
“See if you can find ‘medically necessary’ in my statement,” Guyatt challenged, adding, he’d “have to jump off a bridge if you do.”
This exchange is one of the most fascinating in the history of the transgender issue.
Even though it may be subtle, the guy being interviewed is considered the “founder” of modern evidenced based medicine and recently capitulated to trans activists in a truly embarrassing act… https://t.co/f5sP7L86tF
— Eithan Haim MD (@EithanHaim) September 8, 2025
Hughes later produces the final portion of the statement signed by Guyatt, which reads: “As recommended by community advocates, we have also personally made a donation to Egale Canada’s legal and justice work, noting their litigation efforts aimed at preventing the denial of medically necessary care for gender-diverse youth.”
“That was not my paragraph and I didn’t read carefully, so congratulations,” Guyatt responds.
“You signed something that you didn’t read carefully?” co-host and psychotherapist Stella O’Malley asks.
“Apparently so … What I paid attention to was the part that I wrote,” Guyatt says.
“But you signed a statement with something that very definitely goes against your position?” O’Malley follows up.
“Sorry, but to pick that out, it was in the context of … is inappropriate,” Guyatt continues. “And yeah sure I should’ve read the last line … that part of it was not where my focus was.”
“I was a dope, I’m sometimes a dope,” he said. He then asks the hosts, “Why don’t you just focus on the overall message that I’m giving?”
Guyatt’s “overall message” is hopelessly confused. Guyatt and his team published three studies in 2025 scrutinizing so-called “gender affirming therapy,” including hormone injections and mastectomies.
That’s the father of “evidence based medicine”?! Good Lord. https://t.co/0fjE9Cd1tD
— Rita Panahi (@RitaPanahi) September 8, 2025
Their conclusions were remarkable only in honesty.
One study found that sex changes massively increase suicide risks, rather than reducing them. “Gender-affirming surgery is significantly associated with elevated suicide attempt “risks,” according to that study in the Cureus Journal of Medical Science.
Another study found that “There remains considerable uncertainty regarding the effects of puberty blockers in individuals experiencing [gender dysphoria].” (RELATED: ‘False Appearance Of Consensus’: Medical Establishment Pushes Child Sex Changes Without Evidence, Psychiatrist Says)
From another: “There is considerable uncertainty about the effects of [gender affirming hormone therapy] and we cannot exclude the possibility of benefit or harm.”
Evidence from masectomy case studies “ranged from high to very low certainty” in resolving gender dysphoria, according to Guyatt and his team. Case studies do demonstrate “high-certainty evidence for the outcomes of death, necrosis, and excessive scarring.” “Gender-affirming care” results in permanent and disfiguring changes.
95% of young transgender people on testosterone develop pelvic floor dysfunction; most have bowel issues and sexual dysfunction. As the Telegraph reported, “Around 87 per cent…had urinary symptoms such as incontinence, frequent toilet visits and bed-wetting, while 74 per cent had bowel issues including constipation or being unable to hold stools or wind in. Some 53 per cent suffered from sexual dysfunction…Almost half had an ‘orgasm disorder’, while a quarter suffered from pain during sexual intercourse.”
An FDA official who supported giving minors puberty blockers conceded that they actually increase suicidality. Indeed, the “FDA knew ‘gender affirming’ puberty blockers increase ‘suicidality’ in 2017,” reported Just the News.
For not enthusiastically endorsing the mutilation of teenagers, Guyatt and his team were roundly rebuked by gender activists, prompting the aforementioned statement.
“Members and allies of 2SLGBTQIA+ communities have raised concerns about recent systematic reviews related to gender-affirming care,” the statement begins. “These concerns center on the funding source, and specifically on the potential for the research to be misused to harm trans youth and to deny gender-affirming care.”
Guyatt will probably be better remembered for his cowardice than any contributions to science.
Gender-affirming care doesn’t prevent suicide. The lawyer challenging Tennessee’s ban on certain transgender treatments for minors, Chase Strangio, conceded to the Supreme Court that “completed suicide is thankfully and admittedly rare” among transgender youth, even those not given gender-affirming treatment, and that “there is no evidence…that this treatment reduces completed suicide.
